Area code 251 covers southwestern Alabama, including the city of Mobile and surrounding counties like Baldwin, Escambia, and Washington. Established in 2001 as a split from 334, it serves a region rich in history, culture, and maritime commerce. Mobile, one of the oldest cities on the Gulf Coast, is known for its deep-water port, shipbuilding industry, and Mardi Gras celebrations. It is home to Austal USA, Airbus U.S. Manufacturing Facility, and the University of South Alabama. Tourism also plays a role in the local economy, with Gulf Shores and Orange Beach drawing visitors to Alabama’s small but scenic stretch of coastline. The area has seen steady economic development, particularly in aerospace, healthcare, and logistics. With strong infrastructure and growing business parks, the 251 region offers both Southern charm and industrial strength. A 251 number signals local presence and connection to an area steeped in tradition but open to innovation. Whether you're serving local markets or working with international trade partners, it’s a number that means business on the Gulf Coast.