Area code 864 serves the upstate region of South Carolina, encompassing cities like Greenville, Spartanburg, and Anderson. This area is known for its vibrant manufacturing sector, natural beauty, and rapidly growing economy. Greenville, in particular, has transformed into a modern hub for innovation and business, attracting companies in automotive, aerospace, and advanced manufacturing — with major employers like BMW and Michelin operating nearby. The region is also home to Clemson University, which contributes to the area’s educational and research strengths. The Blue Ridge Mountains to the north offer scenic escapes and recreational opportunities, while the region's affordable cost of living and quality of life attract both retirees and young professionals. 864 is widely recognized across South Carolina as a symbol of the upstate’s resilience and progress. Whether you're launching a tech company or setting up regional services, a number in this area code reflects both credibility and connection in one of the Southeast’s rising markets.